What Is Dakin‑Cooper?
Dakin‑Cooper is a stabilized sodium hypochlorite solution (0.5% active chlorine) in a buffered formula with potassium permanganate—optimized for gentle yet effective antiseptic cleaning of wounds, skin, and mucous membranes. Developed from the historical Carrel–Dakin solution first used in WWI by Henry Dakin and Alexis Carrel .
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How It Works
Broad-spectrum antimicrobial: effective against Gram-positive, Gram-negative, fungi, viruses, spores, MRSA, and VRE .
Debriding action: helps dissolve necrotic tissue via oxidative activity.
Typically used full strength (0.5%) for contaminated or heavily exudative wounds; diluted (0.05–0.025%) for routine cleansing and wet-to-dry dressings .
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Indications
Ideal for:
Wound irrigation and cleansing
Skin and mucous membrane antisepsis (dermatology, gynecology)
Soaking compresses and sitz baths (e.g., perineal hygiene)
Pre/post-surgical site preparation (minor procedures)
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Directions for Use
Apply undiluted for irrigations, washes, compresses, or baths.
Repeat as needed .
Protect surrounding healthy skin with petrolatum to prevent irritation .
Avoid use in eyes, ears with perforation, or open wounds on mucosa without medical advice .
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Safety & Precautions
Side effects: mild burning, redness, stinging—usually reversible .
Tissue toxicity risk with prolonged or high-concentration exposure—monitor fibroblast activity .
Do not use with other antiseptics or occlusive dressings to avoid reduced effectiveness or skin irritation .
Storage: protected from light, sealed, and use promptly after opening to minimize contamination .
Pregnancy/Breastfeeding: Limited systemic absorption; considered safe with medical oversight .
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Practical Tips
Use diluted solution (0.025%) for daily wound cleansing to support healing .
For moderately contaminated wounds, apply undiluted once or twice daily .
Always rinse surrounding skin after application or provide barrier protection.
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Packaging & Availability
Typical bottle sizes: 125 ml, 250 ml, 500 ml, 1 L
Brand: Dakin Cooper Stabilized by Cooper Pharma (France).
Price: around €3–7 for 250 ml; larger bottles proportionally priced .
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Expert Perspective
While Dakin’s antiseptic use has declined with the rise of antibiotics, it remains valuable in cost-effective, broad-spectrum wound care, particularly in chronic or hard-to-heal wounds .
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Conclusion
Dakin‑Cooper Stabilized Solution (0.5% NaOCl) is a reliable and cost-effective antiseptic for cleansing wounds, skin, and mucous membranes. With broad antimicrobial action, gentle debulking properties, and versatile application methods, it remains a trusted option in dermatology and minor procedural care. Use per dosage instructions, protect healthy skin, and monitor for irritation. Consult a professional for chronic wounds or sensitive areas.
